Excellence in Research and Innovation for Humanity

Yan Zhang

Publications

3

Publications

3
2452
An Eulerian Numerical Method and its Application to Explosion Problems
Abstract:
The Eulerian numerical method is proposed to analyze the explosion in tunnel. Based on this method, an original software M-MMIC2D is developed by Cµ program language. With this software, the explosion problem in the tunnel with three expansion-chambers is numerically simulated, and the results are found to be in full agreement with the observed experimental data.
Keywords:
Eulerian method, numerical simulation, shock wave, tunnel
2
10000791
Accurate HLA Typing at High-Digit Resolution from NGS Data
Abstract:

Human leukocyte antigen (HLA) typing from next generation sequencing (NGS) data has the potential for applications in clinical laboratories and population genetic studies. Here we introduce a novel technique for HLA typing from NGS data based on read-mapping using a comprehensive reference panel containing all known HLA alleles and de novo assembly of the gene-specific short reads. An accurate HLA typing at high-digit resolution was achieved when it was tested on publicly available NGS data, outperforming other newly-developed tools such as HLAminer and PHLAT.

Keywords:
Human leukocyte antigens, next generation sequencing, whole exome sequencing, HLA typing.
1
10002702
NSBS: Design of a Network Storage Backup System
Abstract:

The first layer of defense against data loss is the backup data. This paper implements an agent-based network backup system used the backup, server-storage and server-backup agent these tripartite construction, and the snapshot and hierarchical index are used in the NSBS. It realizes the control command and data flow separation, balances the system load, thereby improving efficiency of the system backup and recovery. The test results show the agent-based network backup system can effectively improve the task-based concurrency, reasonably allocate network bandwidth, the system backup performance loss costs smaller and improves data recovery efficiency by 20%.

Keywords:
Agent, network backup system, three architecture model, NSBS.